App Instals w/XP..best way?

Now that I got most the hardware bugs figured...except that anoying mouse acceleration...Im ready to install all my applications.
Should I install the install disk....wait for splash/setup screen...escape/exit...and then go into Windows "Add/Remove Programs" or just install from the install screen?
Im concerned about the "way" it is done. XP didnt exsist before any of my apps. Would It help to prefice the install with the "Add/Remove Programs"?
What do you thinks?
I know some people who insist...."Use Add/Remove to install".
Yet most people throw in the disc and hit install.

If a program has it's own uninstaller, it will be added to the Add/Remove Programs list anyway, regardless of how it is installed.