I use InnoculateIT PE too on my home PC and so far it's saved my setup from quite a number of email viruses, so yah! It works great here too.

I believe that a new version of InnoculateIT PE is due out within a week or so too! Look out for it, it's got much improved real time protection!

Originally posted by QSECOFR:
[B]I use InocualteIT PE. It's free. I'm not 100% sure if it's the best, but for free, you can't complain.