The Security Patch for Outlook 98 and 2000 actually DOES work quite well for killing e-mail based viruses. It deletes ANYTHING executable, regardless of source, content or intention. While this can make transfering files a bit of a hastle, it stops VBS viruses dead in their tracks.

This combined with a good anti-virus program for catching Office macro viruses, and I'm 99.9% protected against viruses through e-mail.