Main things to remember when you're doing a web site is to make it bot friendly.

The bots scan your web page looking for key words, proximity and amount of keywords compared to each other.

You should therefore make sure you incorporate all of the keywords likely to be used in a search on your page or in the META tags on your page.

The title of the page is also scanned too, so make sure this has a few keywords in it too.

Be aware that frames can mess things up - it's always a good idea to put some text, including your keywords, into the <noframes> section of the index page as the bot will scan this.

Finally, submit your site to all the major search engines and get it into DMoz.org as this is where about 99% of the search engines pick their information up from.